Page 2 of 52
Infants born to mothers with autoimmune thyroiditis (AT) could be at risk of developing thyroid dysfunction, and maternal anti-thyroid antibodies have been shown to have a clinical impact on offspring. We aime...
The association between childhood obesity and the early appearance of joint degeneration, particularly in the infrapatellar “Hoffa’s” fat pad, highlights the importance of early diagnosis and treatment. The pu...
This study examines the relationship between early postnatal nutrition, fluid management in preterm infants, and the risk of bronchopulmonary dysplasia (BPD). A comprehensive review was conducted across multip...
This study aimed to analyze the clinical characteristics and differences between neonates with congenital heart disease (CHD)–related neonatal necrotizing enterocolitis (NEC) and those with non-CHD–related neo...
Child nutrition in Ethiopia is a significant concern, particularly for preschool-aged children. Children must have a varied diet to ensure they receive all the essential nutrients for good health. Unfortunatel...
There are some clinical conditions that can impact the accuracy of spO2 measurements, leading to an incorrect diagnosis of hypoxemia. Low oxygen affinity hemoglobinopathy can present with low spO2 and discordance...
This study used two nutritional risk screening (NRS) tools to explore the causal relationship between nutritional risk and clinical outcomes (length of hospital stay and cost), as well as clinical results (inc...
Hypophosphatasia (HPP) is a rare inherited disorder characterized by a deficiency of tissue-non-specific alkaline phosphatase (TNSALP) due to loss-of-function variants of the ALPL gene. HPP is characterized by an...
To validate the role of Activin A in the early diagnosis and prognosis of preterm newborns at risk for intraventricular hemorrhage and neurological sequelae by means of cerebral ultrasound and magnetic resonan...
Childhood hypertension has become a public health problem due to its increasing prevalence and complications; the high prevalence is noted to mirror an increase in obesity among children. Hypertension in child...
Allogeneic hematopoietic stem cell transplantation (HSCT) has proven to be a viable treatment option for patients with mucopolysaccharidoses (MPS). We investigate the efficacy and improvements in the quality o...
Extreme leukocytosis in pertussis is a rare condition, and without effective interventions to reduce white blood cell counts, the mortality rate can approach 100%. The clinical characteristics of these patient...
Bronchopulmonary dysplasia (BPD) frequently occurs in preterm infants, causing significantly impaired lung function and increased mortality rates. Studies on plasma protein levels can facilitate early detectio...
Necrotizing enterocolitis (NEC) is a leading gastrointestinal condition in preterm infants, characterized by significant morbidity and mortality. Early recognition of risk factors is crucial for its prevention...
Management of patients with steroid-sensitive nephrotic syndrome (SSNS) is challenging because of frequent relapses. Causal variants in the human leukocyte antigen (HLA) class II region that are associated wit...
Home mechanical ventilation improves survival of critically ill children but partially affects quality of life. Studies in China have more often analyzed the risk factors for death from prolonged mechanical ve...
The incidence of Type 1 Diabetes (T1D) in children and adolescents is increasing by 3–4% per year. Children and adolescents with T1D (CwD) should receive person-centered, specialized treatment from a multidisc...
Neurodevelopmental disorders such as attention deficit and disruptive behaviour disorders (ADHD), autism spectrum disorder (ASD), and schizophrenia have been increasingly prevalent recently. Previous research ...
The relationship between antenatal corticosteroids (ACS) and preterm infants born to mothers with hypertensive disorders of pregnancy (HDP) remains a subject of debate. To evaluate whether the use of ACS befor...
Acute lymphoblastic leukemia (ALL) is a prevalent hematologic malignancy that primarily affects children. The diagnosis and treatment of pediatric ALL remain challenging. This study aimed to identify different...
This study aimed to compare three different methods [breastfeeding, skin-to-skin contact (SSC), swaddling + holding] to reduce the pain felt by term newborns during a heel lance (HL).
Infectious mononucleosis (IM) is a common disease in children; however, liver injury is its most common complication. However, the pathogenesis of IM complicated with liver injury is ambiguous. Thus, this stud...
Children with congenital lung disease (CLD) may suffer from long-term complications, such as impairments in lung growth, decreased total lung volume, recurrent lower respiratory tract infections and, in some c...
Primary carnitine deficiency (PCD) is a rare autosomal recessive fatty acid oxidation disorder caused by variants in the SLC22A5 gene, with its prevalence and the spectrum of mutations in SLC22A5 varying across r...
Glucocorticoid (GC) response heterogeneity has been recognized as an unfavorable prognostic factor, yet the underlying mechanism remains elusive. In this study, we endeavored to investigate the potential cause...
Evidence shows that earlier access to Antiretroviral Therapy (ART) helps to increase the survival of children by delaying the progression to advanced stages of HIV-related diseases. However, the effect of test...
Currently, there is a lack of data concerning the organization and characteristics of Italian pediatric physiotherapy units for the treatment of patients with chronic lung diseases, especially those with rare ...
Pyruvate dehydrogenase (PDH) deficiency is an uncommon condition responsible for primary refractory lactic acidosis, and PDH E1β (PDHB) subunit gene mutation rarely causes of PDH deficiency. We described a missen...
Congenital ocular anomalies significantly contribute to global disability, with 15–20% of infant blindness attributed to these anomalies. This study examined anophthalmia, microphthalmia, and coloboma (AMC) th...
Early diagnosis of Acute Kidney Injury (AKI) in neonates is a complex challenge. Novel urinary biomarkers such as uNGAL and TIMP-2*IGFBP7 may be helpful for predicting AKI earlier than changes in serum creatin...
Tourette syndrome (TS), a neurological and psychological disease, typically exhibit motor and phonic tics. The pathophysiology of TS remains controversial. Currently, the recognized pathogenesis of TS is the i...
Bronchofiberscopic lavage is a therapeutic treatment for mycoplasma infection. However, there are limited reports on the use of bronchofiberscopic lavage with acetylcysteine instillation. The aim of our study ...
Micafungin, Amphotericin B, and Fluconazole are the primary therapeutic agents employed to address invasive fungal candidiasis in neonates. Resistance to fluconazole is gradually developing in neonatal intensi...
Genetic syndromes resulting from chromosome 18 structural abnormalities constitute a broad spectrum of conditions characterized by significant clinical heterogeneity. Most studies in the literature focus on ca...
Munchausen syndrome by proxy represent forms of abuse with long-term psychiatric outcomes. Since the prevalence of Munchausen Syndrome by proxy is uncertain and underestimated, this study aimed to investigate ...
Childhood morbidity is frequently characterized by more than one health condition. Children under the age of five in low- and middle-income countries including Ethiopia experience multiple episodes of diarrhea...
Cerebral palsy (CP) is a permanent disorder affecting movement and posture due to nonprogressive brain issues, often leading to various sensory, cognitive, and musculoskeletal challenges. Among these complicat...
Kawasaki disease (KD) is a pediatric vasculitis that can lead to coronary artery complications if not promptly diagnosed. Its nonspecific early symptoms, primarily fever, often result in misdiagnosis. This stu...
Pediatric Kawasaki disease (KD) patients showing resistance to intravenous immunoglobulin (IVIG) are at risk of coronary artery lesions; thus, early prediction of IVIG resistance is particularly important. Her...
KBG syndrome (MIM #148050) is a rare genetic disease, showing an autosomal dominant pattern of inheritance. It was first described by Herrmann et al. in 1975 in three affected families, whose initial letters g...
Methemoglobinemia (MetHb) is a rare and potentially life-threatening condition caused by oxidation of ferrous hemoglobin (Fe2+) to the ferric (Fe3+) state, making it incapable of binding oxygen and resulting i...
The relationship between Kawasaki disease (KD) and neurodevelopmental disorders (NDDs) remains unclear. This study aims to explore the association between them.
The aim of the study was to identify the post-traumatic growth status and influencing factors of parents with children with Duchenne muscular dystrophy (DMD).
Acute Otitis Media (AOM) typically affects previously healthy children and can be recurrent. This inter-society consensus aims to provide evidence-based recommendations for the antibiotic therapy of mild, seve...
Enterovirus is a well-known cause of infection in all age groups, with particular importance for neonates with both vertically and horizontally transmission. Neonatal clinical manifestations are highly variabl...
Neonates admitted to neonatal intensive care units (NICUs), as well as maternity nurseries, typically undergo painful invasive procedures during their hospital stay. We aim to report on current bedside analges...
Among the disease-causing genes associated with X-linked intellectual disability (XLID), KDM5C is one of the most frequently mutated ones. KDM5C is a widely expressed gene that is most highly expressed in the bra...
The original article was published in Italian Journal of Pediatrics 2025 51:26
During the pandemic, the pneumology team at Bambino Gesù Children’s Hospital highlighted that telemedicine was a valuable tool for remotely managing the medical needs of children with medical complexity (CMC)....
Drug hypersensitivity reactions (DHRs) in pediatric patients present significant clinical challenges due to their potential for severe, life-threatening reactions such as anaphylaxis. Although less common than...
Citation Impact 2023
Journal Impact Factor: 3.2
5-year Journal Impact Factor: 3.2
Source Normalized Impact per Paper (SNIP): 1.183
SCImago Journal Rank (SJR): 0.799
Speed 2024
Submission to first editorial decision (median days): 24
Submission to acceptance (median days): 139
Usage 2024
Downloads: 2,009,611
Altmetric mentions: 1,949