Table 3 Identified causes of acute flaccid paralysis without myelitis (NM-AFP) for 16 patients
From: Comprehensive analysis of acute flaccid paralysis with and without myelitis in Taiwanese children
Patients (Sex/Age) | Causes | Lesion location or plausible cause | Key Diagnostic Tools or Methods/Characteristics |
|---|---|---|---|
NM-AFP1 (F/16y) | PM | Muscles | MSA panel/ Acute lower limb weakness and pain |
NM-AFP2 (F/12y) | PM | Muscles | MSA panel/ Acute lower limb weakness and pain |
NM-AFP3 (F/16y) | porphyria | Peripheral Neuropathy | urine PGB (+) and NCV (+)/Acute lower limb weakness and moderate abdominal pain |
NM-AFP4 (M/13y) | porphyria | Peripheral Neuropathy | urine PGB (+) /Acute lower limb numbness and serious abdominal pain |
NM-AFP5 (M/10y) | JDM | Muscles | MSA panel and The Bohan and Peter criteria/ whole body proximal weakness and pain |
NM-AFP6 (M/4y) | MG | neuromuscular junction | general muscle weakness and respiratory muscle weakness |
NM-AFP7 (M/7y) | PM | Muscles | MSA panel/ Acute lower limb weakness and pain |
NM-AFP8 (F/10y) | Neuroblastoma | Tumor Compression and Spinal Cord Compression | Imaging Studies confirmation and Tissue Biopsy validation/ Acute lower limb weakness and pain |
NM-AFP9 (F/3y) | PM | Muscles | MSA panel/ Acute lower limb weakness and pain |
NM-AFP10 (F/4y) | MG | neuromuscular junction | AChR-Ab (+) and thymoma detected in chest CT/ptosis |
NM-AFP11 (M/17y) | ALL | Bone Pain and Bone Marrow Infiltration caused by ALL | Initial: Complete Blood Count and Peripheral Blood Smear; Confirmed by Bone Marrow Examination and Flow Cytometry/ Acute lower limb weakness and pain |
NM-AFP12 (F/16y) | GBS | Peripheral Neuropathy | NCV (+) and CSF examination/ Acute lower limb weakness and numbness, loss of DTR |
NM-AFP13 (M/16y) | ALL | Bone Pain and Bone Marrow Infiltration caused by ALL | Initial: Complete Blood Count and Peripheral Blood Smear; Confirmed by Bone Marrow Examination and Flow Cytometry/ Acute lower limb weakness and pain |
NM-AFP14 (M/3y) | Spinal cord injury | C7-T1;T5-T6 | Whole spine MRI and History Taking /Acute Tetraplegia |
NM-AFP15 (M/10y) | hypoPP | Potassium Ion Imbalance resulting in Impaired Muscle Contractility | History Taking and Blood Tests During an Episode/ acute paralysis |
NM-AFP16 (M/12y) | hypoPP | Potassium Ion Imbalance resulting in Impaired Muscle Contractility | History Taking and Blood Tests During an Episode/ acute paralysis |