Skip to main content

Table 3 Adjusted associations between ASD, ADHD, and complications in children admitted for asthma

From: Impact of ASD and ADHD on pediatric asthma exacerbations: a retrospective analysis of the Nationwide Inpatient Sample 2005–2020

Outcomes

Compared with children without ASD or ADHD

ASD alone

ADHD alone

ASD-ADHD

aOR (95% CI)

p-value

aOR (95% CI)

p-value

aOR (95% CI)

p-value

Complications, any

1.44 (1.14–1.82)

0.003

1.05 (0.82–1.35)

0.689

1.69 (1.27–2.26)

< 0.001

 Epilepsy

3.79 (1.79–8.03)

0.001

0.97 (0.37–2.55)

0.956

3.56 (1.61–7.87)

0.002

 Constipation

4.33 (1.78–10.54)

0.001

4.05 (1.65–9.95)

0.002

4.22 (1.58–11.26)

0.004

 Pneumonia

1.69 (1.20–2.39)

0.003

1.11 (0.76–1.61)

0.596

2.00 (1.33–3.03)

0.001

 Sepsis

0.81 (0.32–2.05)

0.652

0.44 (0.15–1.28)

0.130

0.72 (0.18–2.92)

0.641

 Dehydration

0.70 (0.41–1.18)

0.177

0.70 (0.40–1.23)

0.217

0.86 (0.46–1.61)

0.639

 Respiratory Failure/ Mechanical ventilation

0.97 (0.63–1.50)

0.895

0.99 (0.63–1.56)

0.967

1.15 (0.68–1.96)

0.599

 Non-invasive positive pressure ventilation (NIPPV)

0.99 (0.45–2.18)

0.972

1.40 (0.67–2.91)

0.367

0.96 (0.36–2.59)

0.942

  1. Abbreviations: ASD, autism spectrum disorder; ADHD, attention deficit hyperactivity disorder; aOR, adjusted odds ratio; CI, confidence interval
  2. All models were adjusted for related variables of p-value < 0.05 in univariate analysis, including psychiatric comorbidities, medical comorbidities, and year of admission
  3. P-values < 0.05 are shown in bold