Table 1 Demographic and clinical data of the patients
Variable(s) | Total (n = 547) | IVIG-sensitive KD (n = 505, 92.3%) | IVIG-resistant KD (n = 42, 7.6%) | p-value |
|---|---|---|---|---|
Patient characteristics | ||||
Age, months, median (IQR) | 16.5(8.00–31.00) | 16.00(8.25-31.00) | 18.50(7.00–28.00) | 0.649 |
Male sex, n (%) | 337(61.6) | 308(60.9) | 29(69.0) | 0.327 |
weight, kg, median (IQR) | 10.30(8.70-13.43) | 10.30(8.73–13.50) | 10.40(8.40-13.32) | 0.686 |
CAL, n (%) | 105(19.2) | 94(18.6) | 11(26.1) | 0.231 |
Blood biochemical indicators | ||||
ALB, g/L, mean(SD) | 33.57(5.33) | 33.73(5.24) | 31.64(6.00) | 0.039 |
GLB, g/L, mean(SD) | 29.86(6.14) | 29.63(5.77) | 32.56(9.17) | 0.012 |
Creatinine, umol/L, median (IQR) | 35.60(29.55–42.72) | 35.55(29.00-43.18) | 37.65(30.85–40.22) | 0.788 |
ALT, U/L, median (IQR) | 30.00(17.00-88.08) | 29.00(17.00-89.50) | 37.00(18.50–78.33) | 0.481 |
AST, U/L, median (IQR) | 32.00(25.00–51.00 | 32.00(25.00–51.00) | 32.50(23.00-44.50) | 0.804 |
ALT: AST, median (IQR) | 1.18(0.66–1.72) | 1.19(0.67–1.73) | 0.97(0.54–1.58) | 0.252 |
Glucose, mmol/L, median (IQR) | 5.87(5.31–6.54) | 5.88(5.30–6.56) | 5.83(5.26–6.38) | 0.749 |
γ-GT, U/L, median (IQR) | 35.00(15.00–95.00) | 35.00(15.00–93.00) | 65.00(19.00-110.75) | 0.166 |
Blood routine | ||||
Monocyte ratio, %, median (IQR) | 6.98(4.90–9.20) | 6.90(4.90–9.10) | 8.30(5.90–9.88) | 0.124 |
RBC, 10^12/L, median (IQR) | 4.01(3.80–4.30) | 4.03(3.82–4.31) | 3.80(3.23–4.06) | 0.002 |
Eosinophil, 10^9/L, median (IQR) | 2.20(1.10–4.02) | 2.20(1.10–3.99) | 2.70(0.90–5.05) | 0.942 |
HGB, g/L, median (IQR) | 106.00(99.83–112.00) | 107.00(100.00-112.00) | 103.00(88.50-109.25) | 0.019 |
PLT, 10^9/L, median (IQR) | 387.00(310.50-466.33) | 389.00(313.75–466.10) | 365.00(243.25-457.25) | 0.178 |
WBC, 10^9/L, median (IQR) | 14.00(10.98–17.48) | 14.00(10.96–17.49) | 13.93(11.48–17.38) | 0.939 |
NE%, median (IQR) | 60.95(50.00-73.90) | 60.80(49.33–73.98) | 63.40(54.35–71.70) | 0.079 |
Inflammatory indicators | ||||
CRP, mg/L, median (IQR) | 73.16(40.69-105.12) | 74.07(43.28-105.17) | 62.82(32.95–101.90) | 0.258 |
ESR, mm/h, median (IQR) | 59.50(43.75-80.00) | 60.00(44.00-80.750 | 56.00(40.00–70.00) | 0.339 |
Coagulation indicator | ||||
D-Dimer, ng/mL, median (IQR) | 464.50(316.50-615.50) | 463.50(317.50-616.50) | 489.00(257.25–597.50) | 0.551 |
INR, median (IQR) | 1.19(1.11–1.29) | 1.19(1.11–1.29) | 1.16(1.05–1.28) | 0.141 |
TT, sec, median (IQR) | 13.50(12.80–14.30) | 13.50(12.90–14.30) | 13.15(12.57–14.42) | 0.357 |
APTT, sec, median (IQR) | 34.65(31.30-37.53) | 34.79(31.52–37.70) | 32.85(29.68–35.92) | 0.026 |
PT, sec, median (IQR) | 13.50(12.60–14.50) | 13.50(12.60–14.50) | 13.20(12.38–14.92) | 0.357 |
FIB, g/L, median (IQR) | 4.94(4.36–5.44) | 4.94(3.55–5.40) | 4.90(4.29–5.56) | 0.988 |