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Table 1 Demographic, clinical characteristics and neurodevelopmental outcomes of participants

From: Associations between preoperative cerebral white matter microstructural changes and neurodevelopmental deficits in CHD infants: a diffusion tensor imaging study

 

Total(n = 40)

CCHD(n = 20)

ACHD(n = 20)

P value

Demographic characteristics

 

Male sex,%

22(55%)

11(55%)

11(55%)

1.000

Age, m

10.1 ± 4.5

10.1 ± 4.3

10.1 ± 4.9

0.979

SpO2,%

98.0(80.0,100.0)

94.0(80.0,100.0)

100.0(95.0,100.0)

< 0.001*

BW, kg

3.2(1.9,4.0)

3.1(1.9,4.0)

3.2(2.0,4.0)

0.533

Weight at admission, kg

8.5 ± 1.9

8.6 ± 1.6

8.4 ± 2.3

0.719

BMI/age, z-score

-0.07 ± 1.36

0.22 ± 1.26

-0.36 ± 1.43

0.180

WLZ, z-score

-0.03 ± 1.33

0.27 ± 1.19

-0.33 ± 1.42

0.157

WAZ, z-score

-0.23 ± 1.20

-0.11 ± 1.17

-0.34 ± 1.25

0.559

LAZ, z-score

-0.28 ± 1.69

-0.46 ± 1.68

-0.10 ± 1.73

0.508

Clinical characteristics

 

RBC,10^12/L

4.8 ± 0.7

5.2 ± 0.7

4.4 ± 0.5

< 0.001*

HB, g/L

121.0(90.0,178.0)

137.5(90.0,178.0)

116.5(96.0,125.0)

0.009*

Hct,%

37.1(28.6,53.8)

42.4(32.3,53.8)

36.8(28.6,38.1)

0.001*

ALB, g/L

43.3 ± 2.6

42.6 ± 2.4

44.0 ± 2.7

0.112

GLU, mmol/L

4.2(3.2,7.8)

4.1(3.2,4.8)

4.2(3.3,7.8)

0.301

Anatomical parameters of the heart (Maximum diameter during the cardiac cycle)

RA, mm

22.0(18.0,32.0)

21.5(18.0,30.0)

22.5(18.0,32.0)

0.131

RV, mm

14.0(10.0,23.0)

13.0(10.0,17.0)

14.5(10.0,23.0)

0.523

LA, mm

17.0(10.0,27.0)

16.0(10.0,19.0)

17.0(14.0,27.0)

0.007*

LV, mm

23.5(16.0,36.0)

21.5(16.0,27.0)

28.5(20.0,36.0)

< 0.001*

Narrowest inner diameter of the aorta and pulmonary artery

 

AAo, mm

13.1 ± 2.6

14.6 ± 2.5

11.6 ± 1.7

< 0.001*

ARCH, mm

9.2 ± 1.5

10.0 ± 1.4

8.3 ± 1.1

< 0.001*

DAo(diaphragm level), mm

7.1 ± 0.8

7.2 ± 0.7

6.9 ± 0.9

0.200

MPA, mm

13.7 ± 4.4

10.5 ± 3.7

16.9 ± 1.9

< 0.001*

RPA, mm

8.6 ± 2.2

7.2 ± 1.8

10.0 ± 1.5

< 0.001*

LPA, mm

8.0 ± 1.8

6.8 ± 1.5

9.2 ± 1.3

< 0.001*

Preoperative neurodevelopmental outcomes

Adaption behavior

86.569 ± 15.064

80.748 ± 14.133

92.391 ± 13.955

0.013*

Gross motor behavior

83.495 ± 16.660

76.863 ± 12.599

90.126 ± 17.844

0.010*

Fine motor behavior

82.511 ± 16.965

76.079 ± 16.345

88.943 ± 15.380

0.014*

Language behavior

87.795 ± 14.783

82.985 ± 14.522

92.605 ± 13.747

0.038*

Personal-social behavior

91.958 ± 16.528

86.512 ± 16.552

97.404 ± 14.977

0.035*

  1. Data are presented as percentage, mean ± SD or median(range)
  2. SpO2 indicates pulse oxygen saturation; BW, birth weight; RBC, red blood cell; HB, hemoglobin; Hct, hematocrit; ALB, albumin; GLU, glucose; RA, right atrium; RV, right ventricle; LA, left atrium; LV, left ventricle; AAo, ascending aorta; ARCH, aortic arch; DAo, descending aorta; MPA, main pulmonary artery; RPA, right pulmonary artery; LPA, left pulmonary artery
  3. * P < 0.05