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Table 3 Comparison of adverse reaction rates between the two groups

From: Comparison of regional citrate anticoagulation and nafamostat mesylate anticoagulation during plasma exchange for children at high bleeding risk: a retrospective study

Adverse Reaction [n (%)]

RCA-PE Group

n = 45

NM-PE Group

n = 21

P-value

Total Adverse Reactions

29 (64.4)

5 (23.8)

0.003

Bleeding Events

2 (4.4)

1 (4.8)

> 0.999

Metabolic Alkalosis

22 (48.9)

1 (4.8)

< 0.001

Severe Metabolic Alkalosisa

7(15.6)

0(0)

-

Hypocalcemia

2 (4.4)

1 (4.8)

> 0.999

Hypercalcemia

0(0)

0(0)

-

Lactic Acidosis

2 (4.4)

1 (4.8)

> 0.999

Hyperkalemia

1 (2.2)

1 (4.8)

0.538

Hypernatremia

0(0)

0(0)

-

Hyponatremia

0(0)

0(0)

-

  1. RCA: regional citrate anticoagulation; NM: nafamostat mesylate; PE: plasma exchange
  2. a pH > 7.50 and bicarbonate concentration > 30 mmol/L