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Table 2 Characteristics of patients according to outcome

From: Risk factors and mortality in children with severe pertussis: the role of exchange transfusion in a PICU

Variables

Total (n = 170)

Without (n = 131)

With (n = 39)

P

Age (day), M (IQR)

84 (49, 151)

85 (48, 141)

71 (51, 192)

0.732

Gender (male), n(%)

90 (52.94)

73 (55.73)

17 (43.59)

0.183

Immunization, n(%)

76 (44.71)

59 (45.04)

17 (43.59)

0.873

WBC (× 109/l),M (IQR)

32.77 (17.68, 58.25)

25.42 (15.38, 42.33)

66.12 (55.26, 83.10)

 <.001

Lymphocytic absolute value, M (IQR)

15.18 (7.68, 27.20)

12.11 (6.14, 21.66)

28.22 (23.40, 37.78)

 <.001

Neutrophils absolute value, M (IQR)

13.62 (7.20, 23.83)

10.26 (6.29, 16.92)

27.57 (20.33, 39.46)

 <.001

Monocytes absolute value, M (IQR)

1.44 (0.73, 2.80)

1.09 (0.66, 1.94)

2.84 (2.12, 4.57)

 <.001

PLT (× 109/l), M (IQR)

565(466, 708)

548 (446, 690)

620 (527, 743)

0.064

CRP (mg/l), M (IQR)

8 (8, 22)

8 (8, 15)

18 (8, 34)

0.001

PCT (ng/ml), M (IQR)

0.11 (0.07, 0.31)

0.11 (0.07, 0.30)

0.13 (0.08, 0.33)

0.278

Bilirubin (μmol/l), M (IQR)

6.50 (2.00, 13.68)

7.00 (2.00, 13.55)

6.30 (3.00, 13.15)

0.956

Creatinine (μmol/l), M (IQR)

21.50 (17.52, 25.48)

22.00 (18.00, 25.75)

21.00 (16.00, 25.20)

0.162

ALT (U/L), M (IQR)

34.00 (23.85, 47.00)

35.60 (26.25, 48.15)

30.60 (19.50, 42.70)

0.029

PCO2(mmHg), M (IQR)

43.30 (37.00, 52.00)

43.00 (36.50, 50.25)

49.00 (40.40, 55.05)

0.03

PO2(mmHg), M (IQR)

86.40 (65.03, 118.50)

89.10 (67.35, 124.50)

78.20 (61.50, 97.20)

0.142

PH, n(%)

18 (10.59)

15 (11.45)

3 (7.69)

0.709

Epilepsy, n(%)

8 (4.71)

5 (3.82)

3 (7.69)

0.567

Hypoproteinemia, n(%)

74 (43.53)

58 (44.27)

16 (41.03)

0.719

Sepsis, n(%)

27 (15.88)

21 (16.03)

6 (15.38)

0.923

Shock, n(%)

32 (18.82)

13 (9.92)

19 (48.72)

 <.001

Respiratory failure, n(%)

164 (96.47)

127 (96.95)

37 (94.87)

0.903

ARDS, n(%)

12 (7.06)

9 (6.87)

3 (7.69)

1.000

Myocardial injury, n(%)

50 (29.41)

34 (25.95)

16 (41.03)

0.070

ECMO, n(%)

3 (1.76)

3 (2.29)

0 (0.00)

1.000

Hepatic injury, n(%)

34 (20.00)

29 (22.14)

5 (12.82)

0.202

AKI, n(%)

9 (5.29)

6 (4.58)

3 (7.69)

0.723

Other respiratory pathogen infectionsa, n(%)

129 (75.88)

100 (76.34)

29 (74.36)

0.800

Pneumonia, n(%)

165 (97.06)

128 (97.71)

37 (94.87)

0.703

Atelectasis, n(%)

66 (38.82)

54 (41.22)

12 (30.77)

0.240

Lung consolidation, n(%)

121 (71.18)

90 (68.70)

31 (79.49)

0.192

Vasoactive drugs, n(%)

98 (57.65)

69 (52.67)

29 (74.36)

0.016

Albumin, n(%)

124 (72.94)

86 (65.65)

38 (97.44)

 <.001

Hormones, n(%)

98 (57.65)

78 (59.54)

20 (51.28)

0.359

IVIG, n(%)

110 (64.71)

86 (65.65)

24 (61.54)

0.637

Ventilator, n(%)

155 (91.18)

117 (89.31)

38 (97.44)

0.212

High frequency ventilation, n(%)

11 (6.47)

6 (4.58)

5 (12.82)

0.143

Invasive ventilation, n(%)

142 (83.53)

106 (80.92)

36 (92.31)

0.092

Mortality,n (%)

38 (22.35)

22 (16.79)

16 (41.03)

0.001

  1. ALT Alanine transaminase, AKI Acute kidney injury, ARDS Acute respiratory distress syndrome, CRP C-reactive protein, ECMO Extracorporeal membrane oxygenation, IQR Interquartile range, IVIG Intravenous immune globulin, M Median, PCT Procalcitonin, PCO2 Partial pressure of carbon dioxide, PO2 Oxygen partial pressure, PLT Platelet, PH Pulmonary arterial hypertension, WBC White blood cells
  2. aOther respiratory pathogen infections include the following pathogens: Adenovirus, Epstein-Barr Virus, Bocavirus, Parainfluenza Virus, Coronavirus, Respiratory Syncytial Virus, Influenza Virus, Acinetobacter baumannii, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Moraxella catarrhalis, Enterobacter aerogenes, Serratia marcescens, Leminospira nodosa, Methicillin-Resistant Staphylococcus aureus, Elizabethkingia meningoseptica, Klebsiella oxytoca, Achromobacter xylosoxidans, Pseudomonas aeruginosa, Lysinibacillus sphaericus, Candida albicans, Chlamydia pneumoniae, Mycoplasma pneumoniae, Chlamydia, Chlamydia trachomatis, and others