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Table 2 Comparison of single infections with different numbers of co-infections

From: Co-infection in unvaccinated infants with acute pertussis in Western China (2018–2019): pathogen distribution and impact on disease severity

 

Single pertussis infection

One co-infection

Two and more co-infection

P value

121 (40.07%)

134 (44.37%)

47 (15.56%)

Age of onset (day), median (IQR)

81 (13, 293)

74 (14, 353)

78 (22, 340)

0.805

Hospital length of stay, median (IQR)

7 (1, 24)

7.5 (1, 31)

10 (3, 32)

0.001

Gender (female, n, %)

52 (42.98%)

55 (41.04%)

23 (48.94%)

0.643

Pertussis Toxin IgG antibodies, IU/ml, median (IQR)

0.98 (0.00, 170.64)

3.83 (0.00, 219.76)

2.93 (0.00, 167.43)

0.894

WBC count, highest cells×103/µL, median (IQR)

16.75 (6.16, 59.5)

14.12 (4.44, 93.52)

16.68 (7.39, 50.51)

0.699

Lymphocyte count, highest cells×103/µL, median (IQR)

12.48 (2.64, 42.25)

10.03 (3.15, 43.95)

12.4 (2.22, 37.8)

0.172

Raised C-reactive protein (n, %)

1 (0.83%)

13 (9.70%)

2 (4.26%)

/

Raised Procalcitonin (n, %), >0.5 ng/ml

1 (0.83%)

6 (4.48%)

3 (6.38%)

/

Highest respiratory rate (breaths/min)

42 (21, 68)

41 (30, 70)

42 (31, 68)

0.117

Highest heart rate (beats/min)

131 (105, 198)

130 (112, 168)

130 (118, 163)

0.570

Pneumonia (n, %)

91 (75.21%)

101 (75.37%)

41 (87.23%)

0.201

Severe Pneumonia (n, %)

5 (4.13%)

17 (12.69%)

7 (14.89%)

0.028

Respiratory failure (n, %)

5 (4.13%)

15 (11.19%)

7 (14.89%)

0.042