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Table 5 Relationship between birth order and disease determinants

From: Native kidney and graft survival in a cohort of Egyptian children with nephropathic cystinosis: national referral center experience

 

Siblings

P-value

1st sibling

(n = 11)

2nd sibling

(n = 11)

Age at diagnosis/months

 • Mean ± SD

48.64 ± 29.9

29.27 ± 20.1

 = 0.031*

 • Median (IQR)

60 (56)

24 (26)

 

Anthropometrics

 • Underweight

8 (88.9%)

6 (54.5%)

 = 0.026**

 • Stunted

11 (100%)

9 (81.8%)

 = 0.479**

CKD stage

 • Stage-I

1 (9.1%)

1 (9.1%)

 

 • Stage-II

2 (18.2%)

3 (27.3%)

 

 • Stage-III

2 (18.2%)

3 (27.3%)

 = 0.299***

 • Stage-IV

0 (0%)

2 (18.2%)

 

 • Stage-V

6 (54.5%)

2 (18.2%)

 

Outcome

 • Alive

5 (45.5%)

10 (91.9)

 

 • Dead

6 (54.5%)

0 (0%)

 = 0.013***

 • Lost follow up

0 (0%)

1 (9.1%)

 
  1. IQR Inter-Quartile range, SD Standard deviation
  2. *Mann Whitney U test was used to compare the difference in median between groups
  3. **Fisher’s exact test was used to compare the difference in Frequency between groups
  4. ***Monte Carlo exact test was used to compare the difference in Frequency between groups
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Italian Journal of Pediatrics

ISSN: 1824-7288

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