Table 2 Comparison of adverse clinical events before NEC onset between the two groups
nCHD-NEC group (n = 120) | CHD-NEC group (n = 60) | Statistical values | P value | |
|---|---|---|---|---|
Premature rupture of membranes (n, %) | 32(26.7%) | 2(3.3%) | 11.03 | 0.002 |
PDA (n, %) | 32(26.7%) | 44(73.3%) | 19.30 | < 0.001 |
Age at onset (days) | 14.5(12.75,20.75) | 14(9,21) | 0.09 | 0.765 |
Circulatory shock (n, %) | 44(36.7%) | 49(81.7%) | 18.23 | < 0.001 |
Distributive shock | 44(36.7%) | 16(26.7%) | 0.95 | 0.329 |
cardiogenic shock | 8(6.7%) | 38(63.3%) | 26.01 | < 0.001 |
obstructive shock | 0 | 15(25%) | 9.00 | 0.003 |
Mixed shock | 8(6.7%) | 16(26.7%) | 5.00 | 0.025 |
Vasoactive inotropic score | 0(0,10) | 16.75(7.26,23.63) | 17.46 | < 0.001 |
Feeding (n, %) | ||||
breast milk | 4(3.3%) | 0(%) | 2.02 | 0.333 |
Formula | 92(76.7%) | 60(100%) | 15.18 | < 0.001 |
Mixed feeding | 24(20%) | 0(0%) | 12.86 | < 0.001 |
RBC transfusion (n, %) | 96(80.0%) | 49(81.7%) | 0.04 | 1.000 |
Number of erythrocyte transfusions | 2(2,4) | 1(1,1.25) | 26.46 | < 0.001 |
Infusion of red blood cells 48 h before onset (n, %) | 73(60.8%) | 37(61.7%) | 0.24 | 0.943 |
Mechanical ventilation (n, %) | 62(51.7%) | 55(91.7%) | 20.09 | < 0.001 |
Early onset sepsis (n, %) | 28(23.3%) | 4(6.7%) | 5.18 | 0.038 |
Late onset sepsis (n,% ) | 84(70.0%) | 28(46.7%) | 4.39 | 0.036 |
Umbilical vein catheterization (n, %) | 8(6.7%) | 0(0%) | 4.09 | 0.109 |