Glucocorticoid-mediated acetylated regulation of glucocorticoid receptor and Histone3/Histone4 influence glucocorticoid heterogeneity in children patients with primary nephrotic syndrome

Table 1 Comparison of Ac-GR, Ac-H3 and Ac-H4 expressions and NF-κB activity before the GC treatment (\(\:\stackrel{-}{\varvec{x}}\)±s)

group (n)	Ac-GR	Ac-H3	Ac-H4	NF-κB
Control (15)	0.331 ± 0.066	0.401 ± 0.019	0.324 ± 0.034	0.215 ± 0.034
SRNS (15)	0.498 ± 0.113	0.729 ± 0.132	0.664 ± 0.100	0.576 ± 0.064
SSNS (32)	0.429 ± 0.107	0.652 ± 0.126	0.599 ± 0.098	0.397 ± 0.049
F	10.522	27.13	30.87	196.209
p	1.26E-4	3.04E-13	1.14E-16	8.51E-27

Note: The data are presented as mean ± standard deviation (± s). Analysis of variance (ANOVA) was performed to test for differences between the groups, with the F-value serving as the statistical measure for the ANOVA. The p-value is used to determine the statistical significance of the differences (a p-value < 0.05 is considered statistically significant)

ISSN: 1824-7288