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Fig. 2 | Italian Journal of Pediatrics

Fig. 2

From: Glucocorticoid-mediated acetylated regulation of glucocorticoid receptor and Histone3/Histone4 influence glucocorticoid heterogeneity in children patients with primary nephrotic syndrome

Fig. 2

Acetylated H3 expression before (A) and after (B) the GC treatment. The acetylated H3 expression in the SSNS and SRNS groups is higher than that in the control before the GC treatment. The acetylated H3 expression in the SSNS and control groups is lower than that in the SRNS group after the GC treatment. a positive correlation between the NF-κB activity and the Ac-GR protein expression after the GC treatment was found in the SSNS group, in contrast to the negative correlation shown in the SRNS group. The opposite correlations between the NF-κB activity and the Ac-GR protein expression becomes pronounced for the difference in the two groups. A positive correlation for the difference between the Ac-H3 and Ac-H4 expression in the SSNS group, whereas fail to identify such correlation in SRNS

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