Table 1 Comparison of characteristics between CAL and non-CAL in training set
From: Establishment and validation of a predictive model for coronary artery lesions in children with KDSS
Factors | CAD | non-CAD | P-value | |
|---|---|---|---|---|
Demographic parameters | ||||
Number [n (%)] | 24 (33.3) | 48 (66.7) | ‒ | |
Sex (Man/Feman) | 18/6 | 31/17 | 0.431 | |
Age (years) | 5 (3–7) | 4.5 (3–6) | 0.444 | |
BMI (kg/m2) | 15.9 (14.2–19.5) | 15.4 (13.6–17.6) | 0.187 | |
Clinical symptom parameters | ||||
SBP (mmHg) | 76.5 (67.5–81.8) | 80 (75–83) | 0.165 | |
DBP (mmHg) | 40.0 (35.3–47.3) | 40 (36–46) | 0.891 | |
Heart rate | 133 (115–140) | 124 (110–140) | 0.150 | |
Fever days (days) | 10.0 (7.3–14.0) | 7 (7–10) | 0.001 | |
Rash [n (%)] | 19 (79.2) | 40 (83.3) | 0.749 | |
Blood count parameters | ||||
Wbc (1012/L) | 14.8 (11.2–19.0) | 11.7 (8.0-16.8) | 0.089 | |
Low Hgb [n (%)] | 15 (62.5) | 18 (37.5) | 0.045 | |
Plt (109/L) | 241 (138–325) | 185.5 (128.8-281.3) | 0.345 | |
Anc (109/L) | 12.1 (9.1–18.6) | 9.4 (5.6–13.6) | 0.042 | |
CRP (mg/L) | 147.5 (78.5–180.0) | 106.9 (65.8 -144.5) | 0.145 | |
ESR (mm/h) | 88.5 (36.0-94.8) | 62.5 (38.3–90.5) | 0.336 | |
BNP (pg/ml) | 446.6 (121.5-1879.9) | 277.2 (90.1-747.5) | 0.126 | |
HS-cTnI (ng/ml) | 0.012 (0.006–0.061) | 0.011 (0.004–0.037) | 0.760 | |
Blood isochemical parameters | ||||
K (mmol/L) | 3.67 (3.36–4.05) | 3.75 (3.50–3.98) | 0.702 | |
Na (mmol/L) | 132.2 (129.4-135.5) | 130.4 (127.3-133.4) | 0.147 | |
Ca (mmol/L) | 1.99 (1.86–2.15) | 2.05 (1.93–2.14) | 0.492 | |
Low P[n (%)] | 10 (41.7) | 33 (68.9) | 0.027 | |
TP (g/L) | 58.6 (54.5–62.3) | 56.8 (52.9–61.3) | 0.488 | |
ALB (g/L) | 31.9 (25.1–34.7) | 31.9 (28.9–35.4) | 0.430 | |
Cr (umol/L) | 36.7 (26.9–48.8) | 29.9 (22.1–45.6) | 0.221 | |
AST (U/L) | 31.2 (22.9–46.4) | 38.9 (25.9–80.8) | 0.321 | |
ALT (U/L) | 54.7 (21.7-124.2) | 34.8 (18.4-116.7) | 0.485 | |
TBA (umol/L) | 17.8 (7.4-111.9) | 20.5 (9.5–40.2) | 0.914 | |
CG (mg/L) | 4.6 (3.4–45.8) | 7.0 (2.4–14.5) | 0.858 | |
Coagulation parameters | ||||
PT (s) | 13.3 (12.5–15.6) | 13.1 (12.1–14.3) | 0.251 | |
INR | 1.16 (1.10–1.37) | 1.15 (1.07–1.25) | 0.266 | |
FIB (g/L) | 4.97 (3.87–7.12) | 4.58 (3.96–6.18) | 0.201 | |
D-Dimer (mg/L) | 1.01 (0.63–2.82) | 0.99 (0.50–2.08) | 0.298 | |
APTT (s) | 34.9 (30.6–37.5) | 34.3 (31.6–36.9) | 0.519 | |
TT (s) | 14.6 (13.3–15.9) | 14.5 (13.4–15.8) | 0.783 | |
AT-III (%) | 82.5 (66.0–97.0) | 87.5 (74.0–97.0) | 0.607 | |
Inflammatory parameters | ||||
IL-1β | 4.7 (2.4–19.1) | 5.6 (2.5–21.8) | 0.601 | |
IL-2 | 2.4 (2.4–2.8) | 2.4 (2.4–4.5) | 0.072 | |
IL-4 | 2.4 (2.4–2.9) | 2.5 (2.4–4.1) | 0.059 | |
IL-5 | 2.5 (2.4–3.8) | 2.5 (2.4–5.9) | 0.775 | |
IL-6 | 23.2 (7.1-142.5) | 17.5 (6.0-79.9) | 0.379 | |
IL-8 | 4.1 (2.4–9.2) | 8.5 (2.4–35.1) | 0.148 | |
IL-10 | 2.9 (2.4–29.9) | 7.3 (2.5–35.9) | 0.064 | |
IL-12p70 | 2.4 (2.4–2.4) | 2.4 (2.4–2.7) | 0.084 | |
IL-17 | 4.6 (2.4–15.7) | 2.7 (2.4–15.7) | 0.613 | |
TNF | 3.3 (2.4–9.9) | 2.4 (2.4–7.7) | 0.243 | |
α-IFN | 2.4 (2.4–3.6) | 2.4 (2.4–4.1) | 0.442 | |
γ-IFN | 12.7 (2.4–38.2) | 11.7 (4.4-163.8) | 0.419 | |