Clinical significance and pathogenesis of GBP5 in infectious mononucleosis associated liver injury

Table 2 Clinical and laboratory characteristics of IM children with liver and non-liver injuries

Variable	NLIG(n = 30)	LIG(n = 30)	t or χ2 value	p value
Age, years	4.70 ± 2.13	5.70 ± 2.55	−1.66	0.103
Male, n(%)	15(50.0)	12(40.0)	0.61	0.436
Fever (T > 37.3℃), n(%)	27(90.0)	27(90.0)	0.00	1.000
Duration of fever, days	5.43 ± 3.60	6.50 ± 3.87	−1.11	0.273
Hospital stays, days	7.00 ± 2.23	8.23 ± 3.81	−1.53	0.131
WBC,10⁹ /L	14.56 ± 4.69	18.51 ± 6.12	−2.80	0.007
N,10⁹ /L	4.19 ± 2.25	3.74 ± 1.87	0.83	0.410
L,10⁹ /L	8.98 ± 3.56	13.09 ± 4.55	−3.89	< 0.001
M,10⁹ /L	1.31 ± 0.78	1.53 ± 0.94	−0.91	0.368
IgA, g/L	1.65 ± 0.72	1.75 ± 0.71	−0.56	0.580
IgG, g/L	11.30 ± 2.95	11.99 ± 2.64	−0.95	0.344
IgM, g/L	1.64 ± 0.60	1.93 ± 0.57	−1.97	0.054
CD3⁺,%	83.03 ± 6.93	84.97 ± 6.98	−1.08	0.286
CD3⁺CD4⁺,%	18.74 ± 7.20	13.73 ± 5.52	3.02	0.004
CD3⁺CD8⁺,%	51.41 ± 12.00	65.58 ± 7.01	−5.59	< 0.001
CD3⁻CD19⁺,%	5.19 ± 2.28	4.50 ± 4.24	0.78	0.440
CD3⁻CD(16⁺56)⁺,%	10.17 ± 5.38	9.86 ± 4.12	0.25	0.806
LDH, U/L	452.84 ± 81.49	561.35 ± 115.13	−4.21	< 0.001
ALT, U/L	22.11 ± 6.69	224.18 ± 199.12	−5.56	< 0.001
AST, U/L	38.16 ± 7.60	206.98 ± 155.26	−5.95	< 0.001
TBil,µmol/L	5.59 ± 2.01	6.58 ± 3.37	−1.39	0.172
Plasma EBV-DNA lg(copies/ml)	2.94 ± 1.04	3.10 ± 0.95	−0.63	0.531
Whole blood EBV-DNA lg(copies/ml)	5.25 ± 1.07	5.46 ± 0.94	−0.81	0.421

The data were presented as mean ± standard deviation and n (%). The univariate analyses were performed using a t-test for normally distributed and a chi-square test for categorical variables, respectively. Temperature (T), WBC, N, L, M, IgA, IgG, IgM, LDH, ALT, AST, TBil, plasma EBV-DNA and whole blood EBV-DNA were the study variables

ISSN: 1824-7288