Table 1 Laboratory tests at presentation evidenced a severe deficiency of alkaline phosphatase (ALP) and elevated serum phosphorus and vitamin B6 values; other parameters were within normal range
From: Safety and efficacy of long term asfotase alfa treatment in childhood hypophosphatasia
Parameter | Value | Normal range |
|---|---|---|
Red blood cells (106/mm3) | 5.01 | 3.7—5.3 |
Haemoglobin (g/dL) | 12.3 | 11.5—13.5 |
White blood cells (103/µL) | 9.90 | 5—17.5 |
Platelets (103/mm3) | 358 | 300—700 |
Creatinine (mg/dL) | 0.30 | 0.2—0.5 |
Sodium (mmol/L) | 135 | 136—146 |
Potassium (mmol/L) | 4.9 | 3.4—5.10 |
Clorum (mmol/L) | 104 | 98—106 |
Calcium (mmol/L) | 10.4 | 8.5—10.5 |
Phosphorum (mmol/L) | 7.13 | 4.5—6.5 |
AST (UI/L) | 36 | 15—60 |
ALT (UI/L) | 20 | 8—20 |
TSH (µUI/ml) | 2.81 | 0.25—4.5 |
FT4 (ng/dl) | 1.26 | 0.70—1.70 |
PTH (pg/ml) | 23.7 | 8.7—79.6 |
Vitamin D (ng/ml) | 37.7 | 31—100 |
PLP (Vitamin B6) (µg/L) | 383 | 17—70 |
ALP (UI/L) | 20 | 150—700 |