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Table 6 Laboratory data of the studied neonates after 14 days of antifungal treatment

From: Micafungin versus Amphotericin B in treatment of invasive fungal infection in preterm neonates: a randomized control trial

Laboratory data after14 days of treatment

Groups

P value

Sig.

Micafungin

Amphotericin B

N = 28

N = 28

Mean ± SD

Mean ± SD

Bun(mg/dl)

12.5 ± 9.7

21.9 ± 13

0.001

HS

creatinine(mg/dl)

0.3 ± 0.2

0.3 ± 0.1

0.699

NS

Na(mg/dl)

135.6 ± 5.6

138.7 ± 7.2

0.1

NS

K(mg/dl)

4.4 ± 0.9

4.5 ± 0.7

0.335

NS

Calcium(mg/dl)

9.6 ± 0.9

8.9 ± 1.8

0.232

NS

Magnesium(mg/dl)

1.8 ± 0.3

2.4 ± 1

0.018

S

ALT(u/l)

31.2 ± 20.1

72.6 ± 63.2

0.011

S

  1. Mann Whitney U test. BUN: blood urea nitrogen, Na: sodium, K: potassium, ALT: alanine transaminase, N: number of patients, Sig.: significance NS: not significant, (P-value > 0.05), HS: highly significant (P-value < 0.01)