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Table 1 Demographic characteristics, mode of delivery and diagnosis of the studied neonates in both groups

From: Micafungin versus Amphotericin B in treatment of invasive fungal infection in preterm neonates: a randomized control trial

 

Micafungin

N = 28

Amphotericin B

N = 28

P value

Sig.

Mean ± (SD)

Mean ± (SD)

Gestational age (weeks)

34 ± 1.5

33.6 ± 1.9

0.606

NS

Weight (gm)

1885.7 ± 371.6

2197.1 ± 591.7

0.032

S

Length (cm)

42.3 ± 3.5

44.4 ± 3.5

0.09

NS

Head circumference (cm)

30.7 ± 1.8

31.5 ± 2.4

0.189

NS

Patient age at admission (days)

9 ± 9.7

10.4 ± 9.8

0.182

NS

Patient age at onset of fungal infection (days)

29.2 ± 11.2

32.7 ± 24.7

0.974

NS

  

N. (%)

N. (%)

  

Mode of delivery

CS

22 (78.6%)

20 (71.4%)

0.379

NS

NVD

6 (21.4%)

8 (21.4%)

Diagnosis

Surgical

4 (8.3%)

4 (8.2%)

1

NS

RD

10 (20.9%)

11 (22.4%)

0.553

NS

Congenital heart disease

4 (8.3%)

4 (8.2%)

1

NS

Congenital anomalies

8 (16.7%)

12 (24.5%)

0.15

NS

sepsis

22 (78.6%)

18 (64.3%)

0.237

NS

  1. Mann Whitney U test. Chi square test. SD: standard deviation, CS: cesarean section, RD: respiratory distress, NVD: normal vaginal delivery, n: number, (%):percentage. Sig.: significance NS: not significant, (P-value > 0.05), S: significant (P-value < 0.05 ), HS: highly significant (P-value < 0.01)