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Table 1 Comparison of baseline characteristics between the response group and non- response group

From: The association of gene polymorphisms of adenosine and dopamine receptors with the response to caffeine citrate treatment in infants with apnea of prematurity: a prospective nested case-control study

Variables

Total (n = 221)

Non-response group (n = 61)

Response group (n = 160)

Z/X2

P

Maternal age,‾X ± S, years

31.5 ± 4.7

31.5 ± 4.8

31.5 ± 4.7

-0.097

0.923

Gestational diabetes, n (%)

74 (33.5)

24 (39.3)

50 (31.4)

1.232

0.267

Gestational Hypertension, n (%)

33 (14.9)

9 (14.8)

24 (15.0)

0.002

0.963

Chorioamnionitis, n (%)

7 (3.2)

1 (1.6)

6 (3.8)

0.641

0.423

Premature rupture of

membranes > 18 h, n (%)

55 (24.9)

19 (31.1)

36 (22.5)

1.767

0.184

Gestational age, M (Q1, Q3), weeks

32.1 (30.29, 33.29)

30.0 (28.2, 32.3)

31.04 (32.6, 33.4)

-5.446

< 0.001

Birth weight, M (Q1, Q3), grams

1650.0 (1314, 1920)

1313.0 (1016.5, 1652.5)

1742.5 (1479.3, 1965.0)

-5.454

< 0.001

Male, n (%)

123 (55.7)

32 (52.5)

91 (56.9)

0.349

0.555

Cesarean section, n (%)

151 (68.3)

45 (73.8)

106 (66.3)

1.154

0.283

SGA, n (%)

19 (8.6)

7 (11.5)

12 (7.5)

0.888

0.346

Completed antenatal steroids, n (%)

129 (58.4)

38 (62.3)

91 (56.9)

0.534

0.465

5 min Apgar score, M (Q1, Q3)

9 (9,10)

9 (8,9)

9 (9,10)

-3.388

0.001

NRDS, n (%)

64 (29.0)

26 (42.6)

38 (23.8)

7.646

0.006

PDA, n (%)

69 (31.2)

31 (50.8)

38 (23.8)

15.07

< 0.001

  1. SGA: small for gestational age, NRDS: neonatal respiratory distress syndrome, PDA: patent ductus arteriosus