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Table 1 Cardiometabolic risk factors

From: Cardiometabolic risk in children and adolescents with obesity: a position paper of the Italian Society for Pediatric Endocrinology and Diabetology

 

Cut-offs

Weight excess

 

Overall adipositya, b,c

 

0–2 years

 

At risk of overweight

Weight-to-length ratio Z-score > + 1 and <=+2

Overweight

Weight-to-length ratio Z-score > + 2 and <=+3

Obesity

Weight-to-length ratio Z-score > + 3

2–5 years

 

At risk of overweight

BMI Z-score > + 1 and <=+2

Overweight

BMI Z-score > + 2 and <=+3

Obesity

BMI Z-score > + 3

5–18 years

 

Overweight

BMI Z-score > + 1 and <=+2

Obesity

BMI Z-score > + 2 and <=+3

Severe Obesity

BMI Z-score > + 3

Visceral adiposity

 

WHtR

≥ 0.60

High blood pressured

Elevated BP

Systolic and/or diastolic BP (mmHg) ≥ 90th < 95th pc. for age, sex, and height

Hypertension

Systolic and/or diastolic BP (mmHg) ≥ 95th pc. for age, sex, and height (under 16 years) e

 

Systolic and/or diastolic BP (mmHg) ≥ 135/80 (16–18 years)

Glucose dysmetabolism

Prediabetes

 

Impaired fasting glucose

Fasting glucose ≥ 100 < 126 mg/dL

High HbA1c

HbA1c ≥ 5.7 < 6.5% (≥ 39 < 48 mmol/mol)

Impaired glucose tolerance

2-h glucose during oral glucose tolerance test ≥ 140 < 200 mg/dL

Diabetes

Fasting glucose ≥ 126 mg/dL or HbA1c ≥ 6.5% (≥ 48 mmol/mol) or 2-h glucose ≥ 200 mg/dL f

Dyslipidemia

 

High LDL-Cholesterol

LDL- Cholesterol calculated ≥ 130 mg/dL

High cholesterol

Total cholesterol ≥ 200 mg/dL

High triglycerides

Triglycerides ≥ 100 mg/dL (< 10 years) or TG ≥ 130 mg/dL (≥ 10years)

Low HDL-Cholesterol

HDL- Cholesterol <40 mg/dL

Physical inactivity

Physical activity

< 60 min/day

Sedentary behavior

≥ 2 h/day

  1. a Weight-to-length or BMI z-scores of + 1, + 2 and + 3, approximate the 85th, 97th and 99th pcs, respectively
  2. bNormative BMI tables are available from: https://www.who.int/tools/child-growth-standards/standards/weight-for-length-height (0–2 years); https://www.who.int/toolkits/child-growth-standards/standards/body-mass-index-for-age-bmi-for-age (2–5 years); https://www.who.int/tools/growth-reference-data-for-5to19-years (5–18 years)
  3. c software to calculate weight-to-length or BMI percentile or Z-scores is available at http://www.weboriented.it/gh4/downloads/index.php
  4. d Normative systolic and diastolic BP tables arranged by age, sex, and height (and height percentile) [15]
  5. e Confirm on two occasions within 2–3 weeks
  6. f Confirm on two occasions
  7. Abbreviations: BMI: body mass index; BP: blood pressure; HbA1c: glycosylated hemoglobin A1c; HDL: high density lipoprotein; LDL: low density lipoprotein.; pc: percentile