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Table 4 Multiple linear regression of preoperative cardiac structural changes and volume of subcortical nuclei changes in children with TOF

From: Association between subcortical nuclei volume changes and cognition in preschool-aged children with tetralogy of Fallot after corrective surgery: a cross-sectional study

Variables

Preoperative RVOT pressure, mmHg

VSD, mm

Overriding aorta, %

McGoon

LTHA

3.761 (-14.613, 22.136)

-27.101 (-111.221, 57.020)

-165.584 (-4214.907, 3883.740)

153.166 (-636.425, 942.758)

LAM

2.562 (-1.324, 6.448)

-19.828 (-36.462, -3.193)

-407.568 (879.865, 2499.070)

101.039 (-66.857, 268.936)

RTHA

2.474 (-17.560 22.509)

-3.903 (-96.202, 88.397)

503.240 (-3897.615, 4904.096)

88.791 (-772.137, 949.720)

RCAU

-3.257 (-14.464, 7.950)

2.421 (-49.509, 54.351)

2379.803 (102.990, 4656.617)

71.275 (-412.670, 555.220)

RPU

-13.859 (-29.533 1.814)

-50.245 (-124.165, 23.675)

-2074.080 (-5635.641, 1488.482)

693.992 (36.936, 1351.048)

RPA

-0.977 (-6.999, 5.045)

-20.129 (-46.637, 6.380)

-212.272 (-1534.953, 1110.408)

157.500 (-93.515 408.516)

RAM

2.027 (-2.423, 6.476)

-16.816 (-36.463, 2.830)

226.416 (-763.434, 1216.266)

161.462 (-21.271, 344.194)

  1. Data are shown in beta (95% CI). Bold value represents data having statistical significance. Adjusted for sex, BMI, age at MRI and family income
  2. Tetralogy of Fallot, TOF; confidence interval, CI; right ventricular outflow tract, RVOT; ventricular septal defect, VSD; left thalamus proper nucleus, LTHA; left amygdala nucleus LAM; right thalamus proper nucleus, RTHA; right caudate nucleus, RCAU; right putamen nucleus, RPU; right pallidum nucleus, RPA; right amygdala nucleus RAM; body mass index, BMI; magnetic resonance imaging, MRI