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Table 4 Comparison of SBDP145, melatonin, sLOX-1, HMGB1 and HIF-1α levels in infants with different severity of brain white matter injury

From: Evaluation of SBDP145, melatonin, sLOX-1, HMGB1 and HIF-1α in preterm infants with brain injury

Item

Mild (n = 20)

Moderate to severe (n = 12)

t

P

SBDP145(ng/ml)

2.37 ± 0.39

2.91 ± 0.42

-7.691

<0.001

Melatonin(pg/ml)

1081.29 ± 14.01

645.39 ± 14.09

178.124

<0.001

sLOX-1(pg/ml)

403.12 ± 24.02

420.21 ± 25.09

-4.007

<0.001

HMGB1(ng/ml)

71.68 ± 6.08

86.83 ± 6.81

13.591

<0.001

HIF-1α(ng/ml)

1.16 ± 0.23

1.81 ± 0.25

-15.632

<0.001

  1. Note: Mild injury: Grade 0–1; moderate to severe injury: Grade 2–3