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Table 3 Comparison of SBDP145, melatonin, sLOX-1, HMGB1 and HIF-1α levels in infants with different severity of ventricular hemorrhage

From: Evaluation of SBDP145, melatonin, sLOX-1, HMGB1 and HIF-1α in preterm infants with brain injury

Item

Mild (n = 27)

Moderate to severe (n = 19)

t

P

SBDP145(ng/ml)

2.32 ± 0.41

2.98 ± 0.45

-8.864

<0.001

Melatonin(Pg/ml)

1087.65 ± 12.87

632.32 ± 13.92

196.141

<0.001

sLOX-1(pg/ml)

401.03 ± 23.77

421.87 ± 25.21

-4.904

<0.001

HMGB1(ng/ml)

71.29 ± 5.09

87.93 ± 5.03

-18.854

<0.001

HIF-1α(ng/ml)

1.12 ± 0.21

1.83 ± 0.22

-19.016

<0.001

  1. Note: Grade I-II for mild injury; Grade III-IV for moderate to severe injury