Fig. 2

MRI results of Patient 5

One year and ten months old gairl, was admitted for “six days of cough, intermittent fever and convulsions for five days”. On the 8th day of the disease course, the brain MRI showed flaky long T1 (A) and long T2 (B) abnormal signals in the bilateral thalamus, T2 FLAIR (C) had a high signal, and small patchy diffusion restriction (D, E arrows) could be seen in the right thalamus lesion. Diffusion restriction (D ∼ F) could be observed in the bilateral cerebral hemisphere and subcortex, showing “bright tree signs”, indicating cytotoxicoedema. Re-examination of the brain by MRI on the 19th day of the disease showed brain atrophy-like changes in T2 FLAIR images (G), the abnormal signals in the bilateral thalamus had basically disappeared, and the apparent diffusion coefficient (ADC) (H) indicated that there was no restriction of diffusion in the brain