Table 1 Demographics, BAL lipoxin A4 level, ALOX-15, c.292 C> T polymorphism genotypes and alleles distribution in patients and controls
Controls | Patients | OR (95% CI) | P-value | ||
|---|---|---|---|---|---|
N = 30 | N = 30 | ||||
Gender | |||||
Females Males | 16 (53.3%) 14 (46.7%) | 18 (60.0%) 12 (40.0) | - | 0.27* | 0.602 |
Age (years)a | 7.43 ± 2.94 3– 14 | 8.87 ± 3.60 3– 15 | - | -1.68• | 0.097 |
BAL Lipoxin A4 (ng/ml)b | 1675 (536.8– 2542) 370.6– 3876 | 576.9 (147.6– 1501) 68.8– 2352 | - | -3.13† | 0.002 |
ALOX-15 gene polymorphism | |||||
Genotypes, n (%) | |||||
CC CT TT | 14 (46.7%) 8 (26.7%) 8 (26.7%) | 12 (40.0%) 12 (40.0%) 6 (20.0%) | Referent* 1.75 (0.53-5.70) 0.87 (0.23– 3.24) | - 0.353 0.842 | |
Alleles frequency, n (%) | |||||
C T | 36 (60.0%) 24 (40.0%) | 36 (60.0%) 24 (40.0%) | Referent* 1 (0.48 to 2.07) | - 1 | |